Autograft: 100 Years of peer reviewed, published, clinical data
Often maligned by manufacturers of competitive products, no other bone graft material has the efficacy data and safety profile of autologous cancellous bone.
Learn Why Autologous Bone
is the First Choice for Spine Fusions
The Objective of Spinal Fusion
Fusion is a surgical technique used to join two or more vertebrae (bones) within the spine. The objective of a spine fusion is arthrodesis—surgical immobilization of the joint.
Key to immobilization (and successful fusion) is the efficacy of the graft material used between the vertebrae.
What Graft Properties Offer a Better Chance for Successful Spinal Fusion?
Optimal fusion occurs when a graft material contains properties for osteoinduction, osteoconduction, and osteogenesis.
Since autograft contains the greatest amount of the patient’s own bone growing cells and proteins required for osteoinduction, osteoconduction, and osteogenesis (as compared with other alternatives), autograft offers a better chance of acceptance and effectiveness in the transplant site.
The Key Properties Required for Effective Grafts
Osteoinductive
Osteoinductive
Active recruitment and stimulation of stem cells, differentiate into osteoblasts and form new bone.
Osteoconductive
Osteoconductive
Passive scaffold to maintain space and allow for bone formation.
Osteogenic
Osteogenic
Osteogenic living cells, such as osteoblasts, make new bone. Osteoprogenitor cells can proliferate and differentiate to osteoblasts which turn into osteocytes.
Osteoinductive
Active recruitment and stimulation of stem cells, differentiate into osteoblasts and form new bone.
Osteoconductive
Passive scaffold to maintain space and allow for bone formation.
Osteogenic
Osteogenic living cells, such as osteoblasts, make new bone. Osteoprogenitor cells can proliferate and differentiate to osteoblasts which turn into osteocytes.
Autologous Bone Cases and Publications
Autologous Bone Grafting in Trauma and Orthopaedic Surgery: An Evidence-Based Narrative Review
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Percutaneous Harvesting of Cancellous Bone Graft: A Surgical Technique Harvesting from the Calcaneus Using COREX
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Posterior Iliac Crest Bone Graft (ICBG): A Surgical Technique for Harvesting with COREX
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Many approaches are used to repair skeletal defects in reconstructive orthopaedic surgery, and bone grafting is involved in virtually every procedure.
The type of bone graft used depends on the clinical scenario and the anticipated final outcome.
Autogenous cancellous bone graft, with its osteogenic, osteoinductive, and osteoconductive properties, remains the standard for grafting.
Reducing the incidence of morbidity during autogenous graft harvest may make the acquisition of grafts more desirable relative to less effective and more costly alternatives.