Autograft vs Allograft
Learn why autologous bone is superior
and safer than allograft.
Autograft Bone Is One of the Safest Choices
Unlike allografts, the use of autogenous bone graft prevents the risks of disease transmission and graft rejection. In addition, it provides the previously described benefits that translate into faster bone healing.
Better Patient Outcomes
As noted, optimal fusion occurs when a graft material contains properties for osteoinduction, osteoconduction and osteogenesis.
Since autograft contains the greatest amount of the patient’s own bone growing cells and proteins required for osteoinduction, osteoconduction and osteogenesis (as compared with other alternatives), autograft offers a better chance of acceptance and effectiveness in the transplant site.
The Key Properties Required for Effective Grafts
Osteoinductive
Osteoinductive
Active recruitment and stimulation of stem cells, differentiate into osteoblasts and form new bone.
Osteoconductive
Osteoconductive
Passive scaffold to maintain space and allow for bone formation.
Osteogenic
Osteogenic
Osteogenic living cells, such as osteoblasts, make new bone. Osteoprogenitor cells can proliferate and differentiate to osteoblasts which turn into osteocytes.
Osteoinductive
Active recruitment and stimulation of stem cells, differentiate into osteoblasts and form new bone.
Osteoconductive
Passive scaffold to maintain space and allow for bone formation.
Osteogenic
Osteogenic living cells, such as osteoblasts, make new bone. Osteoprogenitor cells can proliferate and differentiate to osteoblasts which turn into osteocytes.
Autologous Bone Cases and Publications
Autologous Bone Grafting in Trauma and Orthopaedic Surgery: An Evidence-Based Narrative Review
Download PDF
Percutaneous Harvesting of Cancellous Bone Graft: A Surgical Technique Harvesting from the Calcaneus Using COREX
View Video